Did they double check? I knew this, and understood it rationally, but when I had two miscarriages in a row I was still devastated because the heart tends to ignore the brain. 2nd pregnancy I had kell antibodies but since Dad is Neg and my pregnancy went on as normal. For one thing, people who are homozygous (KK) for Kell are rare. Thus, all four  children could be kk and Kell positive blood would disappear from their genetic line. I wish we had the $ for the full bloodwork for my husband, as we are only finding put of he is positive or negative for the antigens. If there is no Kell positive fetus/embryo in your uterus then your body won’t be making the anti-Kell stuff to attack it with, so there shouldn’t be enough to show up. My first daughter was born without incident. There are still a lot of issues that medical science doesn’t have all the answers for and there are things they are finding out about blood antigens everyday. Thanks for the answer. I’m O- so had Rhogam shots in all of my pregnancies. I hope I explained why your last healthy baby could have been unknown Kell positive adequately? Now, we’ve all met families where all the kids were the same gender, so you know 50/50 doesn’t mean it will always split down the middle between two outcomes. I am so sorry about the delayed reply. Can you please explain how I would exclude this as our issue, keeping in mind that I am in Eastern Europe and would need to use a common, ‘international’ name for these tests (or maybe go to another country to find them)? If the girl is either Kell positive or negative, it shouldn’t be a problem for her. I can’t take the pressure anymore. Your first born son will need to be tested to know for sure. Since there is only a 50/50 of a first born getting the K gene, maybe only 2 out of the 16 hypothetical grandchildren will be Kell positive. If you get pregnant again you need to be referred to a high risk doctor by 12 wks. This is assuming the blood tests are all correct. Tests get false positives or negatives even when done perfectly by the technicians. We have been trying for years to have a 2nd baby, I have had several misscarriages so those were probably Kell positive babies. You can get the boys tested now and then they can warn their wife/partner if and when pregnancy is a possibility. However, any subsequent pregnancies will be threatened if the fetus is Kell positive. It is fairly certain Mary’s son cannot be Henry’s (the dates the king was near here don’t match up). My ob/gyn also informed me it was not a good idea to have any other pregnancies, and when I had my first back surgery I had to donate blood for myself to be stored. The ABO gene found on chromosome 9 determines the ABO blood group system. This means we can use the Punnett square again and see the genotypes of the offspring of a brown-eyed person (BB or Bb) and a blue-eyed person (bb). Frankly, I am baffled as to how the antibodies got into your system without a blood transfusion or Kk hubby. Remember, YOU are here and you were obviously a Kell+ fetus at one point. What I am also wondering is are the Kell antibodies only detectable if the baby in fact has the antigen, or are they detectable even when basically dormant. But a problem can occur when a Kell-negative mom is somehow exposed to the Kell-positive blood — say, via a blood transfusion. Do you remember the Punnett Square from middle school biology classes? Let’s say mom has brown eyes of BB and dad has blue. Please see Bombay phenotype for a similar situation, these people genetically maybe should be A, or B, but are missing the “foundation” so they don’t express the antigens. I agree with the petition. But my husband did not get tested.and if he is postive why would all my other children be fine and why did it just show up 2 years ago .I had the blood transfusion in 2003 and I have had 3 kids in that time all boys.and I had 3 already before that.could my husband still test postive?I am 15 weeks now with my 8 and my level is high at 1.8? Report as Inappropriate. Yes. (Losing two babies in a row is very common; of every 1000 fertilized eggs 800+ don’t even make it to embryo, so your hormones will frequently “verify” a home pregnancy test based on an implantation that cannot and will not be viable.) Also, multiple miscarriages could have been because of a physiological issue in the mother, as well. I am currently in the same situation and am totally baffled! It says K-k+ is the most common Kell group in Europeans. The presence of Kell antibodies can be detected by maternal blood testing. The test result only means that you did not have COVID-19 at the time of testing. My husband quickly went in to get his blood tested and the results came back today that said he was negative. Thanks so much for this info, it explains so much and I understand it so much better. They would have no K gene to cause their wives any distress during pregnancy. Please STOP advising people that if they are kk, and partner is KK or Kk, they will only be able to have one child that is Kk. That’s right. However, if your husband doesn’t have the Kell gene to give your baby, then your body should have no reason to attack her. Any ideas on where the pos K people are from?? My hubby tested positive for kell antigen and is homogenous for kell so all our kids are kell positive , can you please explain how he is homogenous for kell antigen , my pregnancy is now 34 weeks and my tillers have remained stable at 1:28 but today have doubled , baby shows no signs of anaemia via mca scan and no signs of hydrous but they want to deliver in 2 weeks , what does the rise in antibodies mean? He was K+. I too became anti-kell from a blood transfusion. … I am pregnant and diagnosed as having the anti-Kell antigen. Thank you so much. Random chance works like that. READ MORE. Does this mean my SS2 has a Kell positive blood type and can I get him tested to see? (obsolete) The caul. If you are more worried than you are in love, then end the relationship. Really wish they would screen blood for this when someone donates, it is scary for women to have to go thtough this. I have the very rare Kell Kk polymorphism and had several early miscarriages, at least two of my five adult sons who have been tested are carriers and I have a grandson. Your body recognized the foreign part of the blood (Kell) and built up antibodies to get rid of it… In the same way your body builds up antibodies to get rid of an infection. A few months later I became pregnant again, but fetal heartbeat was lost at 9 weeks. Is that possible? Maybe it is on your post it is pretty late. . The #1 explanation for unknown antibodies is a false positive test or clerical error. I’m 34 years old. They said the last three weeks of pregnancy would almost certainly kill me. Mine was K+k+. I am not a medical doctor, only a medical anthropologist, and I can but speculate that your first born had a K+ blood type and now you have antigens that will attack any K+ tissue, including another Kell+ fetus. Well I am 13 weeks pregnant now, and I just was informed by my doctor that I have the anti-kell antigan. I did have a transfusion. How have I got these antibodies? And after my second one (a week later) I had blood work done and it came back that I had Anti Kell. Should my children be told or even be concerned that they are Kell positive f. A couple of years ago I had a 13 week ultrasound scan for my pregnancy which showed severe fetal hydrops/cystic hygroma, incompatible with life and therefore the pregnancy had to be terminated. … Henry VIII was obese with a years-festering leg wound, gout, maybe a head injury, and on top of that the disposition that comes from being royalty. Which means ONE (which one is anyone’s guess and it would take bloodtyping to find out) of your former pregnancies had a Kell positive fetus. Has he been phenotyped. Hi I have 8 children when I was 20 weeks pregnant with baby number 9 they told me I had kell antibodies and during delivery some of my daughters blood must of leaked back into my system to create antibodies , my husband is father to all my children so is it just pure luck we haven’t had any issues till now? Actually I checked to be notified by email of follow up comments do we’re good. I suggest you get one of the boys (other than the first born) and have him tested for Kell antigens. Either way, your babies are safe from issues due to Kell. The drs will need to do invitro transfusions into the placentas ; however baby A’s is close to her front belly but baby B’s placenta is planted towards her back and that makes it very difficult to perform the transfusions. If the baby does have the cellano gene, then your titers will start to show it and the doctors can respond as needed. If you test negative, you probably were not infected at the time your sample was collected. Does anyone stop to ask what “testing positive for coronavirus” means? How can that be? My husbands waiting to get results to find out if he is kell pos. We did not know anything about this until we were tested for genealogy purposes and I only tested two of my sons, so it would behoove us to get everyone tested as well as my grandson. They were pregnant again but lost the baby at 23 weeks due to the problem. I believe there is a good chance if my son has a Kell blood type that my wife will have K antigens so could you tell me what I should specifically ask the midwife to do regarding this? If two couples, let’s name them Ted (BB) & Alice (bb) and Bob (bb) & Jane (Bb), have children who marry each other then it is possible that all their grandchildren can have blue eyes in spite of the fact that two grandparents have the dominate brown-eyed gene. What do you see as an expert? We also don’t know if the baby is definitely negative if antibodies have shown up in the first place…. READ MORE. I love my wife and my kids, regardless of their origin. You are fine except that if you need a blood transfusion in the future you will have to have blood that is antigen negative for Kell. What does it mean to be “sex positive?” This is one of those terms that different people define in different ways; however, at the core of most definitions is the idea that we must recognize that human sexuality—in its diverse and myriad forms of expression—is natural and healthy. No trouble during that pregnancy. As I am spending a fortune on fertility treatments, and have had every other test in the book done, I would like to find out if the Kell and other antigens/antibodies could have caused the problem. We have patients getting tranfused liters of K+ blood who don’t ever develop antibodies, much less women from their babies. This is how immunohematology is performed on the antigen antibody reaction. Thanks so much for your help.The whole thing is very confusing. To have Kell positive blood means you have at least one of the Kell antigens on your red blood cells. RBcs are packed RBCs they do not contain serum,so with that said RBcs contain antigen. The Kell antibody was introduced into your system, and Daddy is also negative, so as far as I can tell there is no way your son inherited the genes to produce Kell antigens. He would have died had I taken that advice. If you only have two or three children, you may never even have a Kell-effected pregnancy, because you might have the good luck that the babies never get your husband’s genes. I have been wondering if the tables could be turned, could the father produce a K positive baby and mom be k negative. It has NOTHING to do if they are KK, or kk, or Kk. And what about you have you been antigen typed for Kell. Antibodies are found in serum/plasma. Une personne estrhésus positif (+)si ses globules rouges portent, à leur surface, une certaine molécule, appelée molécule rhésus. What I’m not clear on is whether this means I was kell positive from birth and therefore my pregnancy won’t be affected, or kell positive for anti-antigens which I may have picked up from a transfusion during surgery 20 years ago. OB/Gyns tend to overcompensate on preventatives. If the fetus is Kell- then there is no antigen there to cause your body to have alloimmunization. Oh ya, and meant to say that the blood transfusion is how I got the kell. After giving blood twice I recieved a letter letting me know I was A+ kell. My husband has been tested and he is Negative for K (Kell), positive for k (cellano). Because there is a more than 90% chance that one of their parents was Kell negative, and thus had only k genes to bring to the party. I would recommend retesting Dad because a false negative is the most likely explanation. My family scared my and they want me to turn that marriage off, because of the effects of taking “immune globulin intravenous”!! (adsbygoogle = window.adsbygoogle || []).push({}); Post was not sent - check your email addresses! This is called hemolytic disease, and it can be lethal. If you get a non-Kell sperm then (if all else is normal) you will have a healthy pregnancy and a hearty little baby at the end of it without any big medical interventions. I had to get a blood transfusion after. In reference to any weed related matter, often used as a code word. I’ve heard stories of Kell making you severely anemic, and causing women to bleed out even in cases where baby is negative. I feel like even if the baby is negative and so is my husband that there could still be problems with myself? If you are antigen typed and are Kell negative then you have the possibility of formin g antibodies if exposed to the Kell antigen. so far the doctors are thinking that i got this anti-body from the transfusions since we r still waiting on my husbands blood test from last week. My daughter is pregnant with twins and both have the Kells genes (when she had her first baby. That means the partner of the diabetic man is more likely to have miscarriages because the sperm that fertilizes the egg may be “broken”. Once a person has expressed recessive genes, there are NO dominate genes to pass on to their kids. If he is indeed homozygous then I have no idea whatsoever why your other pregnancies didn’t have severe complications. I am anti-k (lowercase) so it is kind of like a cousin to Kell. No worries! Pregnancy is complicated though, so I cannot ‘promise’ you no issues at all. If you are antigen typed and are Kell positive this means you cannot make a antibodies to Kell. Thank you. Stay away from others. My kids were all blood typed as O+. QED — he’s Kell negative. A person can have a specific antibody but at the time of testing it may not be expressing itself and therefore the antibody screen is negative. I see there’s some confusion about Kell vs. Anti-Kell. Not only Rh-, m-n- and KK? I hope their next fetus is Kell- or that the Ob/Gyns can do more to help and keep the fetus safe until old enough to be born. (noun) Dictionary ! I wish I could tell you it would be a-okay from now on but it will depend on several factors. I have had it for two pregnancies ( pregnant with my 5th now, but this issue did not arise until my last pregnancy). And what is an antigen—anything capable of causing a reaction. Actually, the FIRST baby you carry with Kell positive blood is safe … it is all other babies after that first Kell positive baby that are at risk. PLEASE let me know what the results were if you get a son tested for Kell!! you should be fine. Are they overrated or is it a big deal? Your son will be fine . Of course, all of them could have brown eyes – it depends on the roll of the genetic dice when Mr. I’m trying to understand what it means that I’m K+k+. My titers have been low… So everything is fine. Kell is the most agressive antibody. Plasma contains antibodies. It is an X-linked recessive disorder affecting the gene that produces the Kx protein. Hopefully I am going for an ultersound soon to Check blood flow in brain.as I am 17 weeks now. How do we know that if he was Kell positive, Henry had to be Kk and not KK? However, your sibling’s birth is unusual because there should have been enough alloimmunization to effect the pregnancy. There was always speculation that her children were actually Henry VIII’s. In Blood Will Tell I talked about the theory that Henry VIII had a Kell positive blood type, but in my quest to prevent innocent readers from slipping into an over-science coma I didn’t go into deep detail about it. Will this be a health problem for me later in life. This is in addition to the ABO blood groups that most people know about. I am not sure why. Debbie , New York. And yet, 38 years later, here I am. He had some jaundice, and was in an incubator for awhile, but it wasn’t too serious. O-Neg….I appreciate your response have a wonderful day. Anxiety is hard on the mother and fetus too. If the antibody was not being expressed the next time the patient has an antibody screen that screen will be positive. If a mother is found to be Kell positive, the number of antibodies present is determined through the same testing and the mother is given a “score.” This score is referred to as a titer. . After losing two pregnancies, I was blessed with three healthy babies in a row. The B Positive blood type is extremely valuable where matching supply for the demand has been a constant challenge. I understand how it works when the mother is negative and the father is positive. Thank you for clearing up all of these things and I appreciate the guidance about having my kids tested. And even if he DID have the Kell gene, there is lots they could do for his future reproductive partner, and many people with K+ men get lucky and get 3 Kell negative babies in a row. Does this mean anything for the Kell and other antibodies/antigens? Hi there, I just got my first blood test result, it says I have anti K(ell) antibodies. I feel like a blood group freak. If she doesn’t have the anti-Kell antigens, then the pregnancy will have no more risks than the average and you can still go to a midwife. Could you respond by email too because I don’t think I could find this feed again if I tried . Kell is not a blood type. So I got pregnant with triplets in November of last year (I also have a 3 year old daughter). Thanks in advance for any insight you can provide. The baby could miscarry or die of hemolytic disease of the newborn if your wife unknowingly has the anti-Kell antigens and steps aren’t taken. Or maybe none of them will be. I have the same situation as you, during the 6-th pregnancy it appeared I have Kell antigens. Dictionary Thesaurus Examples Sentences Quotes ... ABO blood group incompatibility, and other incompatibilities involving antigens known as Kell, Duffy, M, N, and P, among many others. First, people who are Kell positive are most likely to be Kk instead of KK Why? But these are “irregular antibodies” because they are not fighting against something harmful. I’m already on weekly appointments. I didn’t have them in my first and haven’t had a transfusion. thanks. How likely is it that an OB/GYN would have this on their radar if asked? I will not be having any more children, but am concerned that it may be an issue for them when they have children. Your little girl must be Kell+ and #9 must be Kell+ or your body would not be making antigens. First, I am very sorry for your losses. Yes this will be our 3rd baby together. Your daughter should have no issues (related to blood type) and your son’s partner (if he chooses to have kids as adult and falls in love with a reproductively viable woman!) Egg. (Yes, even five in a row. Does that mean I got this from my parents? Even if he does happen to be kell positive (very unlikely) then your baby will still be safe since you don’t have anti-kell antibodies. Hi, Not sure why this came to mind but it dis, perhaps I’m trying to occupy my time while we wait for the blood work. But my levels of it were too weak to show up on the titer level. (Ack! I wonder if my blood type is actually a connector, although according to the heredity patterns, could the Kk have survived through a father line? Looking for a shoulder to cry on while I go through this process. Le signe + ou - correspond au rhésus. For this reason, Kell typing of the father is the primary step in the management of Kell disease in pregnancy. My ancestry is all European (mainly British) but my Kell result is K+k+ (and also Kp(a-b+)). This blood type is present in about 33% in Caucasians, 24% in African American, 29% in Hispanic, and 27% in Asian. I have three children. Would I be safe assuming that my first daughter would be kk and my son kk and my youngest child Kk ? Okay, I’m trying to remember science in middle school, having a tough time. My second child, my son, had mild haemolytic disease of the newborn. (Well, it used to be like that before modern medical treatments that will keep a Kell positive fetus alive inside a Kell negative mother. However, not all of the ethnic groups share the same proportions of A positive blood types. Okay, the GOOD news is that as a K+ woman your pregnancies will never be effected. Dominate browns can easily be hiding secret blue genes (insert blue jean joke here) but the brown B is gone once the recessive have the field. Le système Rhésus est un système complexe qui comporte plusieurs antigènes dont le plus important pour la transfusion est l’antigène D. Sur les globules rouges des sujets dits Rhésus négatifs l’antigène D n’est pas présent alors qu’il l’est chez les sujets Rhésus positif. Did you ever gather any more information on where your antibodies came from? You are still A+ blood type (as am I). Those antigens can doge a test more than people realize. But how did Henry get that Kell positive gene? Your husband would be the one who is Kell positive. Take brown eyes and blue eyes, for example. During the immune response, the woman's body recognises that the RhD positive blood cells are foreign and creates antibodies to destroy them. So of you are Kk, then are you positive or negative? It is rare my midwife said to find blood compatible with Kell. I wrote you earlier, but my blog didn’t post it. Anti-K antibodies, for example, bind to the 'Kell antigen' on red blood cells. That’s where antigens are located in the red blood cells. Also I think maybe some people are getting g mixed up on this sight. I’m the first child of my parents (Kk, my father is KK, my mother is kk). I had my first two babies via midwife, so I understand the desire for a low-intervention pregnancy and delivery, but if your wife has the anti-Kell antigens then the pregnancy is officially high risk and will need to go the full biomedical intervention route. Or would the kell positive woman still need medical advice/help to conceive and carry to term? Any university would probably have such an expert that you could email. This post will provide a tad more information as to what it is exactly and how it is transmitted. After all, it is a 50/50 shot, so you have an equal chance of non-Kell genes. Un groupe sanguin comprend une lettre A, B ou O et un signe + ou –. There are apparently quite a few antigenic things that can be running around on the surface of your red blood cells. Please, I need help, I have to make a decision within a day. I really REALLY hope that modern medical intervention keeps you and your current baby healthy. I’d be worried about the antibodies that you contracted not the antigen Kell. I was wondering if the woman above ever figured out any answers as to how she contracted the antibody? Okay, the odds that your bloodwork gave a false negative is MUCH higher than the odds of any kids being not yours. I’m also going to add a futer amnio should be done by a MFM @ 15-18 wks. It will be a normal pregnancy, like your last one. You should now take the advice from a MFM vs an OB. If they’re present, your doc will closely monitor your pregnancy through blood tests and ultrasounds. I sincerely hope all goes well! They did a titer all they told me was that it is an 8 ?…. I have never had a blood transfusion and was A+ all my life until after baby #1. I hope this pregnancy and any future pregnancies go smoothly and without complications! Nor is she is a drug user. I wish I could tell you that yes he could be in her blood the... 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